| 2. Round | 14/08/2021 | Árabe Unido | - | Tauro FC | 0:1 | ||||
| 3. Round | 21/08/2021 | Sporting San Miguelito | - | Tauro FC | 1:0 | ||||
| 6. Round | 12/09/2021 | San Francisco FC | - | Tauro FC | 1:3 | ||||
| 7. Round | 19/09/2021 | Atlético Chiriquí | - | Tauro FC | 0:1 |  |
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| 8. Round | 26/09/2021 | Tauro FC | - | Herrera FC | 1:1 | ||||
| 9. Round | 03/10/2021 | Tauro FC | - | UD Universitario | 3:1 | ||||
| 10. Round | 10/10/2021 | Independiente de La Chorrera | - | Tauro FC | 1:0 | ||||
| 11. Round | 16/10/2021 | Tauro FC | - | Veraguas Club Deportivo | 2:0 | ||||
| 12. Round | 24/10/2021 | Plaza Amador | - | Tauro FC | 1:2 | ||||
| 14. Round | 07/11/2021 | Tauro FC | - | Sporting San Miguelito | 1:0 |
Panama