| 2. Round | 17/04/2022 | AFA Olaine | - | FK Smiltene | 1:2 | ||||
| 4. Round | 30/04/2022 | Riga FC II | - | FK Smiltene | 3:0 | ||||
| 5. Round | 08/05/2022 | FK Smiltene | - | Valmiera FC II | 2:3 | ||||
| 7. Round | 22/05/2022 | FK Smiltene | - | Rēzeknes FA | 3:3 | ||||
| 8. Round | 28/05/2022 | FS Jelgava | - | FK Smiltene | 1:0 | ||||
| 9. Round | 19/06/2022 | FK Smiltene | - | Grobiņas SC | 0:4 | ||||
| 11. Round | 16/07/2022 | FK Smiltene | - | FK Dinamo Rīga | 1:0 | ||||
| 13. Round | 30/07/2022 | FK Smiltene | - | FK Tukums 2000 II | 1:3 | ||||
| 15. Round | 21/08/2022 | FK Smiltene | - | AFA Olaine | 0:3 | ||||
| 17. Round | 03/09/2022 | FK Smiltene | - | Riga FC II | 0:5 | ||||
| 18. Round | 10/09/2022 | Valmiera FC II | - | FK Smiltene | 5:0 | ||||
| 19. Round | 18/09/2022 | FK Smiltene | - | Rīgas Futbola skola II | 1:7 | ||||
| 20. Round | 01/10/2022 | Rēzeknes FA | - | FK Smiltene | 5:2 | ||||
| 21. Round | 09/10/2022 | FK Smiltene | - | FS Jelgava | 0:5 | ||||
| 22. Round | 16/10/2022 | Grobiņas SC | - | FK Smiltene | 7:2 | ||||
| 23. Round | 22/10/2022 | FK Smiltene | - | Saldus SS/Leevon | 0:2 | ||||
| 24. Round | 30/10/2022 | FK Dinamo Rīga | - | FK Smiltene | 1:1 | ||||
| 25. Round | 05/11/2022 | FK Smiltene | - | JDFS Alberts | 0:1 | ||||
| 26. Round | 13/11/2022 | FK Tukums 2000 II | - | FK Smiltene | 1:2 |
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