| 3. Round | 31/01/2025 | Municipal Limeño | - | Isidro Metapán | 0:0 | ||||
| 6. Round | 13/02/2025 | Isidro Metapán | - | Dragón | 2:1 | ||||
| 8. Round | 23/02/2025 | Isidro Metapán | - | Luis Ángel Firpo | 0:0 | ||||
| 9. Round | 26/02/2025 | CD Águila | - | Isidro Metapán | 2:0 | ||||
| 14. Round | 27/03/2025 | Isidro Metapán | - | Municipal Limeño | 0:0 |  |
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| 15. Round | 29/03/2025 | CD Cacahuatique | - | Isidro Metapán | 0:0 | ||||
| 16. Round | 06/04/2025 | Isidro Metapán | - | Platense Zacatecoluca | 2:1 | ||||
| 17. Round | 09/04/2025 | Dragón | - | Isidro Metapán | 2:3 | ||||
| 18. Round | 13/04/2025 | Isidro Metapán | - | FAS | 3:1 |  |
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| 20. Round | 24/04/2025 | Isidro Metapán | - | CD Águila | 2:2 | ||||
| 21. Round | 27/04/2025 | Alianza | - | Isidro Metapán | 1:0 |
El Salvador