| 1. Round | 26/02/2022 | Mineros de Guayana | - | Monagas | 1:3 | ||||
| 4. Round | 17/03/2022 | Carabobo FC | - | Mineros de Guayana | 3:1 | ||||
| 5. Round | 26/03/2022 | Mineros de Guayana | - | Aragua FC | 0:3 | ||||
| 7. Round | 10/04/2022 | Mineros de Guayana | - | Academia Puerto Cabello | 2:0 | ||||
| 8. Round | 17/04/2022 | Metropolitanos FC | - | Mineros de Guayana | 5:0 |
Venezuela