| 1. Round | 10/07/2022 | Cienciano | - | Universidad Cesar Vallejo | 2:0 | ||||
| 2. Round | 15/07/2022 | Deportivo Municipal | - | Cienciano | 0:0 | ||||
| 6. Round | 07/08/2022 | Cienciano | - | Universitario de Deportes | 1:0 |  |
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| 7. Round | 14/08/2022 | Sport Boys | - | Cienciano | 2:1 | ||||
| 8. Round | 20/08/2022 | Cienciano | - | Atlético Grau | 2:2 | |
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| 9. Round | 28/08/2022 | Alianza Atlético | - | Cienciano | 1:0 | ||||
| 10. Round | 03/09/2022 | Cienciano | - | Mannucci | 2:0 | ||||
| 11. Round | 11/09/2022 | Sporting Cristal | - | Cienciano | 4:1 | ||||
| 12. Round | 17/09/2022 | Cienciano | - | FBC Melgar | 2:2 | ||||
| 14. Round | 04/10/2022 | Cienciano | - | Sport Huancayo | 0:1 | ||||
| 15. Round | 07/10/2022 | Universidad Técnica | - | Cienciano | 2:1 | |
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| 17. Round | 20/10/2022 | Academia Cantolao | - | Cienciano | 3:1 | ||||
| 18. Round | 24/10/2022 | Cienciano | - | Carlos Stein | 6:2 | ||||
| 19. Round | 30/10/2022 | Universidad San Martín | - | Cienciano | 1:2 |
Argentina
Peru