| 1. Round | 25/02/2023 | Independiente del Valle | - | Mushuc Runa | 3:1 | ||||
| 2. Round | 05/03/2023 | Mushuc Runa | - | Gualaceo SC | 2:1 | ||||
| 3. Round | 18/03/2023 | Guayaquil City | - | Mushuc Runa | 4:1 | ||||
| 4. Round | 01/04/2023 | Barcelona | - | Mushuc Runa | 1:0 | ||||
| 5. Round | 09/04/2023 | Mushuc Runa | - | Libertad de Loja | 2:1 | ||||
| 6. Round | 16/04/2023 | Delfín SC | - | Mushuc Runa | 3:0 | ||||
| 7. Round | 24/04/2023 | Mushuc Runa | - | Emelec | 0:0 |
Argentina