| 10. Round | 18/09/2022 | Atlético Chiriquí | - | Sporting San Miguelito | 0:0 |  |
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| 11. Round | 24/09/2022 | Independiente de La Chorrera | - | Sporting San Miguelito | 0:2 | ||||
| 12. Round | 28/09/2022 | Alianza | - | Sporting San Miguelito | 1:0 | ||||
| 13. Round | 02/10/2022 | Sporting San Miguelito | - | Plaza Amador | 1:1 | |
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| 14. Round | 08/10/2022 | Árabe Unido | - | Sporting San Miguelito | 1:1 | ||||
| 15. Round | 17/10/2022 | Tauro FC | - | Sporting San Miguelito | 2:0 |
Panama