| 1. Round | 06/07/2015 | New York Cosmos | - | Indy Eleven | 1:1 | ||||
| 1. Round | 12/07/2015 | Indy Eleven | - | Carolina RailHawks | 2:1 |  |
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| 1. Round | 19/07/2015 | Ottawa Fury | - | Indy Eleven | 4:2 | ||||
| 1. Round | 26/07/2015 | Indy Eleven | - | New York Cosmos | 1:1 |  |
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| 2. Round | 09/08/2015 | Indy Eleven | - | Ottawa Fury | 1:4 | ||||
| 2. Round | 20/08/2015 | Indy Eleven | - | Tampa Bay Rowdies | 2:0 | |
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| 2. Round | 23/08/2015 | Atlanta Silverbacks | - | Indy Eleven | 1:1 | |
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| 3. Round | 03/09/2015 | Minnesota United FC | - | Indy Eleven | 1:0 | ||||
| 3. Round | 06/09/2015 | Indy Eleven | - | Jacksonville Armada | 3:0 | ||||
| 3. Round | 13/09/2015 | San Antonio Scorpions | - | Indy Eleven | 2:0 | ||||
| 3. Round | 20/09/2015 | Indy Eleven | - | FC Edmonton | 0:2 | ||||
| 4. Round | 01/10/2015 | Tampa Bay Rowdies | - | Indy Eleven | 1:1 | ||||
| 4. Round | 11/10/2015 | Indy Eleven | - | San Antonio Scorpions | 1:2 | ||||
| 4. Round | 18/10/2015 | Indy Eleven | - | Minnesota United FC | 3:1 | ||||
| 4. Round | 25/10/2015 | Indy Eleven | - | Fort Lauderdale Strikers | 2:1 | ||||
| 4. Round | 30/10/2015 | Carolina RailHawks | - | Indy Eleven | 3:1 |
Honduras