| Round of 16 | 21/04/2022 | Atlético Junior | - | Santa Fe | 2:1 |  |
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| Round of 16 | 12/05/2022 | Santa Fe | - | Atlético Junior | 0:1 | |
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| Quarter-finals | 29/07/2022 | Atlético Junior | - | Atlético Nacional | 3:0 | ||||
| Quarter-finals | 19/08/2022 | Atlético Nacional | - | Atlético Junior | 1:1 | ||||
| Semi-finals | 25/08/2022 | Atlético Junior | - | Unión Magdalena | 0:1 | ||||
| Semi-finals | 15/09/2022 | Unión Magdalena | - | Atlético Junior | 0:1 pso |  |
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| Final | 29/09/2022 | Atlético Junior | - | Millonarios | 1:0 | |
Argentina