| 1. Round | 22/07/2018 | Danubio | - | Progreso | 2:2 | ||||
| 2. Round | 28/07/2018 | Defensor Sporting | - | Danubio | 1:2 | ||||
| 3. Round | 04/08/2018 | Danubio | - | Racing | 1:1 | ||||
| 4. Round | 12/08/2018 | River Plate | - | Danubio | 1:2 | ||||
| 5. Round | 18/08/2018 | Danubio | - | Montevideo Wanderers | 2:2 | ||||
| 6. Round | 26/08/2018 | Liverpool | - | Danubio | 3:0 | ||||
| 8. Round | 09/09/2018 | Boston River | - | Danubio | 0:0 | ||||
| 9. Round | 16/09/2018 | Danubio | - | Peñarol | 0:2 |
Uruguay