| 3. Round | 05/11/2021 | Smouha Sporting Club | - | El Sharkia Lel Dokhan | 3:0 | ||||
| 4. Round | 19/11/2021 | ENPPI | - | Smouha Sporting Club | 1:1 | ||||
| 6. Round | 25/11/2021 | Al Ahly SC | - | Smouha Sporting Club | 4:1 | ||||
| 7. Round | 21/12/2021 | Smouha Sporting Club | - | Ismaily | 2:1 | ||||
| 5. Round | 25/12/2021 | Smouha Sporting Club | - | Tala'ea El Gaish SC | 1:0 | ||||
| 22. Round | 17/06/2022 | Tala'ea El Gaish SC | - | Smouha Sporting Club | 3:3 | ||||
| 25. Round | 17/07/2022 | Smouha Sporting Club | - | National Bank SC | 0:1 | ||||
| 26. Round | 24/07/2022 | Zamalek | - | Smouha Sporting Club | 2:0 | ||||
| 27. Round | 27/07/2022 | Smouha Sporting Club | - | Al Mokawloon | 1:1 | ||||
| 28. Round | 31/07/2022 | Ghazl Al Mehalla | - | Smouha Sporting Club | 1:0 | ||||
| 33. Round | 26/08/2022 | Misr lel-Maqasah SC | - | Smouha Sporting Club | 0:2 |
Egypt