| 1. Round | 07/04/2021 | Rangers | - | Unión San Felipe | 3:1 | ||||
| 2. Round | 18/04/2021 | San Luis | - | Rangers | 0:1 | ||||
| 3. Round | 26/04/2021 | Rangers | - | Deportes Copiapó | 2:3 | ||||
| 4. Round | 02/05/2021 | Universidad de Concepción | - | Rangers | 3:2 | ||||
| 5. Round | 11/05/2021 | Rangers | - | Barnechea | 2:0 | ||||
| 6. Round | 18/05/2021 | CD Magallanes | - | Rangers | 0:1 | ||||
| 7. Round | 24/05/2021 | Santiago Morning | - | Rangers | 0:0 |  |
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| 8. Round | 02/06/2021 | Rangers | - | Puerto Montt | 0:0 | |
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| 12. Round | 21/07/2021 | Coquimbo Unido | - | Rangers | 1:1 | ||||
| 13. Round | 01/08/2021 | Rangers | - | Deportes Iquique | 1:0 | ||||
| 14. Round | 08/08/2021 | San Marcos | - | Rangers | 1:0 | ||||
| 15. Round | 16/08/2021 | Rangers | - | Cobreloa | 4:0 | |
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| 16. Round | 23/08/2021 | Unión San Felipe | - | Rangers | 2:1 | ||||
| 23. Round | 04/10/2021 | Puerto Montt | - | Rangers | 3:1 | ||||
| 24. Round | 09/10/2021 | Fernández Vial | - | Rangers | 2:2 | |
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| 25. Round | 14/10/2021 | Rangers | - | Deportes Temuco | 0:2 | ||||
| 26. Round | 19/10/2021 | Santa Cruz | - | Rangers | 1:0 | |
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| 27. Round | 24/10/2021 | Rangers | - | Coquimbo Unido | 0:1 | ||||
| 29. Round | 06/11/2021 | Rangers | - | San Marcos | 1:1 | ||||
| 30. Round | 13/11/2021 | Cobreloa | - | Rangers | 4:1 |
Argentina