| 21. Round | 06/03/2021 | Rotor Volgograd | - | FK Khimki | 0:0 | ||||
| 22. Round | 12/03/2021 | FK Khimki | - | FK Rostov | 1:0 | ||||
| 23. Round | 19/03/2021 | Rubin Kazan | - | FK Khimki | 1:3 |  |
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| 24. Round | 05/04/2021 | Zenit St. Petersburg | - | FK Khimki | 2:0 | ||||
| 25. Round | 10/04/2021 | FK Khimki | - | FK Tambov | 1:0 | ||||
| 26. Round | 17/04/2021 | Akhmat Grozny | - | FK Khimki | 3:1 | ||||
| 27. Round | 24/04/2021 | Dinamo Moskva | - | FK Khimki | 0:1 | |
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| 28. Round | 02/05/2021 | FK Khimki | - | FK Ural | 1:0 | ||||
| 29. Round | 10/05/2021 | Spartak Moskva | - | FK Khimki | 2:1 | ||||
| 30. Round | 16/05/2021 | FK Khimki | - | FK Sochi | 0:0 |
Sweden