| 7. Round | 14/10/2016 | Arsenal FC U23 | - | Southampton FC U23 | 0:0 | ||||
| 8. Round | 24/10/2016 | Southampton FC U23 | - | Manchester City U23 | 0:3 | ||||
| 9. Round | 31/10/2016 | Derby County U23 | - | Southampton FC U23 | 2:0 | ||||
| 10. Round | 21/11/2016 | Chelsea FC U23 | - | Southampton FC U23 | 3:2 | ||||
| 11. Round | 28/11/2016 | Southampton FC U23 | - | Everton FC U23 | 1:1 | ||||
| 15. Round | 16/01/2017 | Southampton FC U23 | - | Arsenal FC U23 | 1:3 | ||||
| 17. Round | 06/02/2017 | Leicester City U23 | - | Southampton FC U23 | 0:2 | ||||
| 22. Round | 21/04/2017 | Southampton FC U23 | - | Derby County U23 | 0:1 | ||||
| 13. Round | 05/05/2017 | Manchester City U23 | - | Southampton FC U23 | 4:2 |
Romania