| 2. Round | 24/07/2021 | Alianza Atlético | - | Sport Huancayo | 1:0 | ||||
| 3. Round | 31/07/2021 | Universidad Cesar Vallejo | - | Alianza Atlético | 2:0 | ||||
| 6. Round | 13/08/2021 | Alianza Atlético | - | FBC Melgar | 3:3 | ||||
| 7. Round | 19/08/2021 | Alianza Atlético | - | Alianza Universidad | 1:2 | ||||
| 9. Round | 28/08/2021 | Alianza Atlético | - | Mannucci | 2:0 |  |
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| 10. Round | 12/09/2021 | Sporting Cristal | - | Alianza Atlético | 5:2 | ||||
| 11. Round | 17/09/2021 | Alianza Atlético | - | Cienciano | 2:2 | ||||
| 12. Round | 21/09/2021 | Ayacucho FC | - | Alianza Atlético | 0:1 | ||||
| 13. Round | 25/09/2021 | Alianza Atlético | - | Alianza Lima | 1:3 | ||||
| 14. Round | 01/10/2021 | Sport Boys | - | Alianza Atlético | 3:1 | ||||
| 15. Round | 16/10/2021 | Alianza Atlético | - | Academia Cantolao | 3:1 | ||||
| 16. Round | 23/10/2021 | Universidad San Martín | - | Alianza Atlético | 3:1 | |
Peru