| Preliminary | 29/07/2022 | Real Estelí FC | - | Real España | 0:0 | ||||
| Preliminary | 05/08/2022 | Real España | - | Real Estelí FC | 3:1 | ||||
| Round of 16 | 18/08/2022 | Real España | - | CS Cartaginés | 2:0 | ||||
| Round of 16 | 25/08/2022 | CS Cartaginés | - | Real España | 0:2 | ||||
| Quarter-finals | 09/09/2022 | Real España | - | CS Herediano | 3:1 | ||||
| Quarter-finals | 16/09/2022 | CS Herediano | - | Real España | 1:1 | ||||
| Semi-finals | 05/10/2022 | Real España | - | LD Alajuelense | 0:3 | ||||
| Semi-finals | 12/10/2022 | LD Alajuelense | - | Real España | 2:2 |  |
Honduras