| 2. Round | 26/01/2021 | Tigres FC | - | Unión Magdalena | 1:1 | ||||
| 1. Round | 03/02/2021 | Fortaleza FC | - | Tigres FC | 2:0 | ||||
| 4. Round | 07/02/2021 | Tigres FC | - | Deportes Quindío | 1:1 | ||||
| 6. Round | 15/02/2021 | Tigres FC | - | Orsomarso SC | 2:0 | ||||
| 8. Round | 28/02/2021 | Tigres FC | - | Boca Juniors de Cali | 1:1 | ||||
| 13. Round | 27/03/2021 | Valledupar FC | - | Tigres FC | 0:0 |
Colombia