| 1. Round | 25/10/2020 | Costa del Este FC | - | Sporting San Miguelito | 2:1 | ||||
| 2. Round | 29/10/2020 | Árabe Unido | - | Sporting San Miguelito | 1:2 | ||||
| 4. Round | 14/11/2020 | Alianza | - | Sporting San Miguelito | 1:0 | ||||
| 5. Round | 18/11/2020 | Sporting San Miguelito | - | San Francisco FC | 1:2 | ||||
| 6. Round | 21/11/2020 | Sporting San Miguelito | - | Plaza Amador | 0:1 | ||||
| 9. Round | 07/12/2020 | Sporting San Miguelito | - | Independiente de La Chorrera | 0:2 |
Panama