| 1. Round | 16/01/2022 | Once Municipal | - | FAS | 1:1 | ||||
| 2. Round | 23/01/2022 | FAS | - | CD Águila | 0:3 | ||||
| 3. Round | 26/01/2022 | Jocoro FC | - | FAS | 2:2 | ||||
| 12. Round | 13/03/2022 | FAS | - | Once Municipal | 0:0 | ||||
| 13. Round | 20/03/2022 | CD Águila | - | FAS | 2:0 | ||||
| 16. Round | 10/04/2022 | Santa Tecla FC | - | FAS | 1:1 |  |
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| 19. Round | 24/04/2022 | FAS | - | Isidro Metapán | 4:1 | |
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| 20. Round | 28/04/2022 | AD Chalatenango | - | FAS | 3:2 |
El Salvador