| 1. Round | 20/08/2022 | PAOK Saloniki | - | Panetolikos | 1:0 | ||||
| 2. Round | 28/08/2022 | Panetolikos | - | Aris Saloniki | 3:1 | ||||
| 3. Round | 04/09/2022 | Atromitos | - | Panetolikos | 1:1 | ||||
| 4. Round | 10/09/2022 | OFI Heraklion | - | Panetolikos | 1:2 | ||||
| 5. Round | 17/09/2022 | Panetolikos | - | AEK Athen | 0:2 | ||||
| 6. Round | 03/10/2022 | PAS Giannina | - | Panetolikos | 1:4 | ||||
| 11. Round | 06/11/2022 | Panetolikos | - | Levadiakos | 0:0 | ||||
| 12. Round | 09/11/2022 | Panetolikos | - | Panathinaikos | 0:1 | ||||
| 13. Round | 13/11/2022 | Lamia | - | Panetolikos | 1:3 | ||||
| 14. Round | 22/12/2022 | Panetolikos | - | PAOK Saloniki | 0:2 | ||||
| 15. Round | 29/12/2022 | Aris Saloniki | - | Panetolikos | 1:0 | ||||
| 16. Round | 04/01/2023 | Panetolikos | - | Atromitos | 2:0 | ||||
| 17. Round | 09/01/2023 | Panetolikos | - | OFI Heraklion | 0:4 | ||||
| 18. Round | 15/01/2023 | AEK Athen | - | Panetolikos | 4:1 | ||||
| 19. Round | 20/01/2023 | Panetolikos | - | PAS Giannina | 1:1 |
Greece