| 1. Round | 28/08/2022 | APOEL Nikosia | - | Paphos FC | 1:1 | ||||
| 2. Round | 04/09/2022 | Anorthosis Famagusta | - | APOEL Nikosia | 0:2 | ||||
| 4. Round | 17/09/2022 | Olympiakos Nikosia | - | APOEL Nikosia | 0:2 |  |
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| 5. Round | 02/10/2022 | APOEL Nikosia | - | AEL Limassol | 0:0 | ||||
| 6. Round | 07/10/2022 | APOEL Nikosia | - | Karmiotissa Polemidion | 0:0 | ||||
| 7. Round | 16/10/2022 | Akritas Chlorakas | - | APOEL Nikosia | 1:2 | ||||
| 9. Round | 30/10/2022 | Apollon Limassol | - | APOEL Nikosia | 0:1 | ||||
| 11. Round | 13/11/2022 | Doxa Katokopias | - | APOEL Nikosia | 0:1 | ||||
| 12. Round | 27/11/2022 | APOEL Nikosia | - | Omonia Nikosia | 4:0 | ||||
| 13. Round | 03/12/2022 | Nea Salamina | - | APOEL Nikosia | 1:3 |  |
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| 15. Round | 17/12/2022 | APOEL Nikosia | - | Anorthosis Famagusta | 1:0 | |
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| 16. Round | 22/12/2022 | Aris Limassol | - | APOEL Nikosia | 1:1 | ||||
| 17. Round | 03/01/2023 | APOEL Nikosia | - | Olympiakos Nikosia | 1:0 | |
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| 18. Round | 08/01/2023 | AEL Limassol | - | APOEL Nikosia | 1:0 | |
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| 20. Round | 22/01/2023 | APOEL Nikosia | - | Akritas Chlorakas | 2:0 | |
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| 23. Round | 11/02/2023 | Enosis Neon Paralimni | - | APOEL Nikosia | 1:2 |
Cyprus