| 14. Round | 31/01/2021 | Mamelodi Sundowns | - | Chippa United | 2:0 | ||||
| 23. Round | 21/04/2021 | AmaZulu FC | - | Mamelodi Sundowns | 0:0 | ||||
| 24. Round | 25/04/2021 | Mamelodi Sundowns | - | Kaizer Chiefs | 1:2 | ||||
| 25. Round | 28/04/2021 | Mamelodi Sundowns | - | Golden Arrows | 0:0 | ||||
| 26. Round | 02/05/2021 | Orlando Pirates | - | Mamelodi Sundowns | 0:3 | ||||
| 16. Round | 05/05/2021 | Mamelodi Sundowns | - | Maritzburg United | 2:0 |  |
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| 27. Round | 09/05/2021 | TS Galaxy | - | Mamelodi Sundowns | 0:1 | ||||
| 29. Round | 02/06/2021 | Bloemfontein Celtic | - | Mamelodi Sundowns | 0:2 |
South Africa