| 1. Round | 30/07/2011 | KV Kortrijk | - | Lierse SK (old) | 1:1 | ||||
| 5. Round | 27/08/2011 | KAA Gent | - | Lierse SK (old) | 1:0 | ||||
| 6. Round | 10/09/2011 | Lierse SK (old) | - | Sporting Lokeren | 1:1 | ||||
| 7. Round | 17/09/2011 | Cercle Brugge | - | Lierse SK (old) | 0:0 |  |
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| 10. Round | 15/10/2011 | SV Zulte Waregem | - | Lierse SK (old) | 1:2 | ||||
| 11. Round | 22/10/2011 | Lierse SK (old) | - | Sint-Truidense VV | 0:2 | ||||
| 13. Round | 05/11/2011 | Lierse SK (old) | - | Oud-Heverlee Leuven | 3:1 |  |
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| 14. Round | 19/11/2011 | RAEC Mons | - | Lierse SK (old) | 2:1 | ||||
| 15. Round | 26/11/2011 | Lierse SK (old) | - | Club Brugge KV | 0:1 | ||||
| 16. Round | 03/12/2011 | Lierse SK (old) | - | KV Mechelen | 2:2 | ||||
| 17. Round | 10/12/2011 | KRC Genk | - | Lierse SK (old) | 4:0 | ||||
| 19. Round | 26/12/2011 | Beerschot AC | - | Lierse SK (old) | 0:0 | ||||
| 22. Round | 25/01/2012 | Lierse SK (old) | - | Cercle Brugge | 2:2 | ||||
| 24. Round | 04/02/2012 | Lierse SK (old) | - | Standard Liège | 0:2 | ||||
| 25. Round | 11/02/2012 | Lierse SK (old) | - | SV Zulte Waregem | 2:1 | ||||
| 27. Round | 26/02/2012 | Lierse SK (old) | - | RSC Anderlecht | 0:0 | ||||
| 30. Round | 21/03/2012 | Club Brugge KV | - | Lierse SK (old) | 1:0 |
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