| 4. Round | 30/07/2021 | Tacoma Defiance | - | San Diego Loyal | 2:1 | ||||
| 5. Round | 02/08/2021 | Los Angeles Galaxy II | - | San Diego Loyal | 0:2 | ||||
| 5. Round | 15/08/2021 | San Diego Loyal | - | Tacoma Defiance | 1:2 | ||||
| 5. Round | 19/08/2021 | San Diego Loyal | - | Las Vegas Lights FC | 5:1 | ||||
| 5. Round | 22/08/2021 | San Diego Loyal | - | Orange County SC | 1:2 | ||||
| 5. Round | 29/08/2021 | Sacramento Republic | - | San Diego Loyal | 1:3 |
Kenya
Somalia