| 1. Round | 25/07/2010 | CS Sfaxien | - | Olympique Béja | 0:0 |  |
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| 2. Round | 04/08/2010 | ES Hammam Sousse | - | CS Sfaxien | 0:1 |  |
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| 3. Round | 21/08/2010 | CS Sfaxien | - | CA Bizertin | 1:0 | ||||
| 4. Round | 22/09/2010 | Espérance Zarzis | - | CS Sfaxien | 0:0 | ||||
| 5. Round | 26/09/2010 | CS Sfaxien | - | EGS Gafsa | 1:1 | ||||
| 6. Round | 21/10/2010 | Espérance de Tunis | - | CS Sfaxien | 3:1 | ||||
| 7. Round | 24/10/2010 | AS Gabès | - | CS Sfaxien | 0:1 | |
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| 9. Round | 20/11/2010 | AS Marsa | - | CS Sfaxien | 1:2 | ||||
| 8. Round | 08/12/2010 | CS Sfaxien | - | Stade Tunisien | 1:1 | ||||
| 11. Round | 12/12/2010 | JS Kairouan | - | CS Sfaxien | 2:1 | ||||
| 12. Round | 19/12/2010 | CS Sfaxien | - | CS Hammam-Lif | 3:1 | |
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| 15. Round | 17/04/2011 | CS Sfaxien | - | ES Hammam Sousse | 2:1 | |
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| 17. Round | 01/05/2011 | CS Sfaxien | - | Espérance Zarzis | 1:1 | ||||
| 18. Round | 22/05/2011 | EGS Gafsa | - | CS Sfaxien | 1:0 |
Tunisia