| 2. Round | 28/10/2020 | Orlando Pirates | - | Stellenbosch FC | 1:1 | ||||
| 3. Round | 04/11/2020 | Bloemfontein Celtic | - | Orlando Pirates | 0:1 | ||||
| 8. Round | 13/01/2021 | Tshakhuma FC | - | Orlando Pirates | 0:3 | ||||
| 11. Round | 17/01/2021 | Black Leopards | - | Orlando Pirates | 2:0 | ||||
| 12. Round | 20/01/2021 | Orlando Pirates | - | Golden Arrows | 0:0 |  |
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| 13. Round | 23/01/2021 | Maritzburg United | - | Orlando Pirates | 0:1 | ||||
| 15. Round | 26/01/2021 | Orlando Pirates | - | TS Galaxy | 1:1 | ||||
| 14. Round | 30/01/2021 | Orlando Pirates | - | Kaizer Chiefs | 2:1 | ||||
| 16. Round | 02/02/2021 | Golden Arrows | - | Orlando Pirates | 2:0 | ||||
| 19. Round | 09/02/2021 | Orlando Pirates | - | Cape Town City FC | 2:0 | ||||
| 21. Round | 24/02/2021 | SuperSport United | - | Orlando Pirates | 1:1 | ||||
| 17. Round | 02/03/2021 | Orlando Pirates | - | Bloemfontein Celtic | 1:0 | ||||
| 18. Round | 06/03/2021 | Chippa United | - | Orlando Pirates | 0:3 | ||||
| 29. Round | 02/06/2021 | Baroka FC | - | Orlando Pirates | 1:2 | |
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| 30. Round | 05/06/2021 | Orlando Pirates | - | Tshakhuma FC | 0:0 |
South Africa