| 3. Round | 29/08/2021 | Royal Excel Mouscron | - | Waasland-Beveren | 0:4 | ||||
| 9. Round | 22/10/2021 | Royal Excel Mouscron | - | RWD Molenbeek | 1:1 | ||||
| 11. Round | 06/11/2021 | Royal Excel Mouscron | - | SK Deinze | 2:0 | ||||
| 14. Round | 05/12/2021 | KVC Westerlo | - | Royal Excel Mouscron | 4:3 | ||||
| 18. Round | 30/01/2022 | RWD Molenbeek | - | Royal Excel Mouscron | 2:0 |  |
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| 19. Round | 05/02/2022 | Royal Excel Mouscron | - | Waasland-Beveren | 3:0 | ||||
| 20. Round | 12/02/2022 | KVC Westerlo | - | Royal Excel Mouscron | 1:0 | ||||
| 23. Round | 06/03/2022 | Royal Excel Mouscron | - | RWD Molenbeek | 0:1 | ||||
| 24. Round | 13/03/2022 | Lierse Kempenzonen | - | Royal Excel Mouscron | 0:1 | ||||
| 25. Round | 18/03/2022 | Royal Excel Mouscron | - | SK Deinze | 1:2 | |
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| 26. Round | 03/04/2022 | Excelsior Virton | - | Royal Excel Mouscron | 2:0 | |
France
Ivory Coast