| Group D | 26/03/2021 | Panama | - | Barbados | 1:0 | ||||
| Group D | 28/03/2021 | Dominica | - | Panama | 1:2 | ||||
| Group D | 09/06/2021 | Panama | - | Dom. Republic | 3:0 | ||||
| 2. Round | 13/06/2021 | Panama | - | Curaçao | 2:1 | ||||
| 2. Round | 16/06/2021 | Curaçao | - | Panama | 0:0 | ||||
| 3. Round | 08/10/2021 | El Salvador | - | Panama | 1:0 | ||||
| 3. Round | 10/10/2021 | Panama | - | USA | 1:0 | ||||
| 3. Round | 14/10/2021 | Canada | - | Panama | 4:1 | ||||
| 3. Round | 30/01/2022 | Panama | - | Jamaica | 3:2 | ||||
| 3. Round | 31/03/2022 | Panama | - | Canada | 1:0 |  |
Panama