| 3. Round | 19/03/2022 | AEL Limassol | - | Omonia Nikosia | 1:1 | ||||
| 4. Round | 04/04/2022 | Omonia Nikosia | - | PAEEK | 4:2 | ||||
| 5. Round | 08/04/2022 | Olympiakos Nikosia | - | Omonia Nikosia | 3:0 | ||||
| 1. Round | 20/04/2022 | Ethnikos Achna | - | Omonia Nikosia | 0:0 | ||||
| 10. Round | 20/05/2022 | Omonia Nikosia | - | Olympiakos Nikosia | 1:1 |
Spain