| 1. Round | 21/09/2020 | Valletta FC | - | Birkirkara FC | 4:2 | ||||
| 2. Round | 26/09/2020 | Balzan FC | - | Valletta FC | 0:1 | ||||
| 3. Round | 30/09/2020 | Valletta FC | - | Gżira United | 1:3 | ||||
| 4. Round | 18/10/2020 | Hibernians FC | - | Valletta FC | 1:1 |  |
|||
| 6. Round | 25/10/2020 | St. Luċija FC | - | Valletta FC | 1:1 | ||||
| 7. Round | 01/11/2020 | Valletta FC | - | Senglea Athletics | 2:1 | ||||
| 8. Round | 21/11/2020 | Gudja United | - | Valletta FC | 0:0 | ||||
| 5. Round | 24/11/2020 | Valletta FC | - | Sirens FC | 1:1 | ||||
| 9. Round | 29/11/2020 | Tarxien Rainbows | - | Valletta FC | 3:1 | ||||
| 17. Round | 22/01/2021 | Valletta FC | - | Balzan FC | 1:0 | |
|||
| 14. Round | 27/01/2021 | Valletta FC | - | Hamrun Spartans | 0:3 | ||||
| 18. Round | 31/01/2021 | Gżira United | - | Valletta FC | 2:0 | ||||
| 15. Round | 03/02/2021 | Valletta FC | - | Sliema Wanderers | 0:0 | ||||
| 19. Round | 07/02/2021 | Valletta FC | - | Hibernians FC | 1:4 | ||||
| 20. Round | 14/02/2021 | Sirens FC | - | Valletta FC | 0:1 |  |
|||
| 23. Round | 07/03/2021 | Valletta FC | - | Gudja United | 2:4 |
Malta