| 2. Round | 29/07/2017 | Gallos Blancos | - | Lobos BUAP | 0:4 | ||||
| 3. Round | 05/08/2017 | Lobos BUAP | - | CF Pachuca | 3:2 |  |
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| 4. Round | 13/08/2017 | Pumas UNAM | - | Lobos BUAP | 2:0 | ||||
| 5. Round | 19/08/2017 | Lobos BUAP | - | CF América | 2:3 | ||||
| 6. Round | 23/08/2017 | Atlas Guadalajara | - | Lobos BUAP | 1:1 | ||||
| 7. Round | 27/08/2017 | UANL Tigres | - | Lobos BUAP | 3:2 | ||||
| 8. Round | 09/09/2017 | Lobos BUAP | - | Monarcas Morelia | 1:3 | ||||
| 9. Round | 18/09/2017 | CD Veracruz | - | Lobos BUAP | 0:1 | ||||
| 11. Round | 27/09/2017 | Deportivo Guadalajara | - | Lobos BUAP | 1:2 | ||||
| 12. Round | 30/09/2017 | Lobos BUAP | - | Club León | 0:3 | ||||
| 13. Round | 12/10/2017 | Deportivo Toluca | - | Lobos BUAP | 3:1 | ||||
| 10. Round | 18/10/2017 | Lobos BUAP | - | Club Tijuana | 1:2 | ||||
| 14. Round | 21/10/2017 | Lobos BUAP | - | Cruz Azul | 3:0 | ||||
| 15. Round | 29/10/2017 | Club Necaxa | - | Lobos BUAP | 5:0 | ||||
| 16. Round | 04/11/2017 | Lobos BUAP | - | CF Monterrey | 2:1 | ||||
| 17. Round | 18/11/2017 | Puebla FC | - | Lobos BUAP | 0:1 |
Mexico