| 18. Round | 24/04/2021 | Ittihad El Iskandary | - | Pyramids FC | 0:2 | ||||
| 20. Round | 06/05/2021 | Ittihad El Iskandary | - | Al Ahly SC | 1:2 | ||||
| 21. Round | 09/05/2021 | ENPPI | - | Ittihad El Iskandary | 0:0 | ||||
| 23. Round | 20/05/2021 | Al Masry Club | - | Ittihad El Iskandary | 1:0 |  |
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| 24. Round | 25/05/2021 | Ittihad El Iskandary | - | El Gouna | 0:1 | ||||
| 25. Round | 28/05/2021 | Aswan SC | - | Ittihad El Iskandary | 0:2 | ||||
| 26. Round | 17/06/2021 | Ittihad El Iskandary | - | Misr lel-Maqasah SC | 2:1 | ||||
| 27. Round | 25/06/2021 | Ghazl Al Mehalla | - | Ittihad El Iskandary | 1:1 | ||||
| 28. Round | 05/07/2021 | Ismaily | - | Ittihad El Iskandary | 1:2 | ||||
| 29. Round | 10/08/2021 | Ittihad El Iskandary | - | Zamalek | 1:2 | ||||
| 30. Round | 13/08/2021 | Wadi Degla SC | - | Ittihad El Iskandary | 0:0 | ||||
| 31. Round | 17/08/2021 | Ittihad El Iskandary | - | Ceramica Cleopatra | 0:0 | ||||
| 32. Round | 21/08/2021 | El Entag El Harby | - | Ittihad El Iskandary | 1:1 | ||||
| 33. Round | 24/08/2021 | Ittihad El Iskandary | - | National Bank SC | 0:0 | ||||
| 34. Round | 28/08/2021 | Al Mokawloon | - | Ittihad El Iskandary | 1:3 |
Egypt