| 2. Round | 27/10/2021 | Espérance de Tunis | - | CS Sfaxien | 1:0 | ||||
| 4. Round | 03/11/2021 | CS Sfaxien | - | US Tataouine | 1:0 | ||||
| 5. Round | 06/11/2021 | ES Hammam Sousse | - | CS Sfaxien | 0:0 |  |
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| 8. Round | 03/03/2022 | ES Métlaoui | - | CS Sfaxien | 2:1 |  |
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| 9. Round | 06/03/2022 | CS Sfaxien | - | Espérance de Tunis | 1:0 | ||||
| 10. Round | 09/03/2022 | CS Sfaxien | - | US Ben Guerdane | 0:1 | ||||
| 11. Round | 16/03/2022 | US Tataouine | - | CS Sfaxien | 0:0 | ||||
| 13. Round | 10/04/2022 | CA Bizertin | - | CS Sfaxien | 2:0 |
Algeria