| 8. Round | 10/10/2021 | Olympique Marseille [Youth] | - | Toulouse FC [Youth] | 0:1 | ||||
| 9. Round | 17/10/2021 | FC Istres [Youth] | - | Olympique Marseille [Youth] | 3:3 | ||||
| 10. Round | 24/10/2021 | Olympique Marseille [Youth] | - | Pieve di Lota [Youth] | 5:0 | ||||
| 11. Round | 14/11/2021 | AS Monaco [Youth] | - | Olympique Marseille [Youth] | 2:1 | ||||
| 12. Round | 21/11/2021 | Olympique Marseille [Youth] | - | US Colomiers [Youth] | 2:0 | ||||
| 14. Round | 05/12/2021 | Olympique Marseille [Youth] | - | Montpellier HSC [Youth] | 1:2 | ||||
| 19. Round | 06/03/2022 | Olympique Marseille [Youth] | - | OGC Nice [Youth] | 4:1 | ||||
| 20. Round | 20/03/2022 | Toulouse FC [Youth] | - | Olympique Marseille [Youth] | 0:0 | ||||
| 21. Round | 27/03/2022 | Olympique Marseille [Youth] | - | FC Istres [Youth] | 1:0 | ||||
| 23. Round | 10/04/2022 | Olympique Marseille [Youth] | - | AS Monaco [Youth] | 1:4 |
France