| 18. Round | 06/01/2022 | Persipura Jayapura | - | Persela Lamongan | 1:1 | ||||
| 19. Round | 11/01/2022 | Persija Jakarta | - | Persipura Jayapura | 1:2 | ||||
| 25. Round | 14/02/2022 | PS Barito Putera | - | Persipura Jayapura | 3:0 | ||||
| 26. Round | 18/02/2022 | Persipura Jayapura | - | Persib Bandung | 0:3 | ||||
| 27. Round | 24/02/2022 | Bali United | - | Persipura Jayapura | 4:1 | ||||
| 31. Round | 16/03/2022 | Bhayangkara Presisi Indonesia | - | Persipura Jayapura | 1:2 | ||||
| 32. Round | 20/03/2022 | Persipura Jayapura | - | PSS Sleman | 4:2 | ||||
| 33. Round | 24/03/2022 | PSIS Semarang | - | Persipura Jayapura | 0:4 | ||||
| 34. Round | 31/03/2022 | Persita Tangerang | - | Persipura Jayapura | 0:3 |
Indonesia