| 3. Round | 14/08/2010 | Standard Liège | - | Sporting Lokeren | 3:3 | ||||
| 4. Round | 21/08/2010 | Sporting Lokeren | - | RSC Anderlecht | 0:3 | ||||
| 11. Round | 16/10/2010 | Sporting Charleroi | - | Sporting Lokeren | 1:2 | ||||
| 12. Round | 24/10/2010 | Sporting Lokeren | - | Club Brugge KV | 1:0 | ||||
| 13. Round | 30/10/2010 | SV Zulte Waregem | - | Sporting Lokeren | 1:1 | ||||
| 14. Round | 06/11/2010 | Lierse SK (old) | - | Sporting Lokeren | 2:2 | ||||
| 15. Round | 13/11/2010 | Sporting Lokeren | - | Sint-Truidense VV | 3:0 | ||||
| 19. Round | 12/12/2010 | RSC Anderlecht | - | Sporting Lokeren | 0:0 | ||||
| 22. Round | 30/12/2010 | Sporting Lokeren | - | KRC Genk | 2:2 |  |
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| 25. Round | 06/02/2011 | Germinal Beerschot | - | Sporting Lokeren | 1:1 | ||||
| 21. Round | 16/02/2011 | KVC Westerlo | - | Sporting Lokeren | 1:2 |  |
Senegal
Bulgaria