| 2. Round | 15/08/2020 | Sporting Charleroi | - | KV Oostende | 1:0 | ||||
| 3. Round | 24/08/2020 | Sint-Truidense VV | - | KV Oostende | 0:0 | ||||
| 4. Round | 28/08/2020 | KV Oostende | - | RSC Anderlecht | 2:2 | ||||
| 7. Round | 28/09/2020 | KRC Genk | - | KV Oostende | 2:2 | ||||
| 8. Round | 04/10/2020 | KV Oostende | - | Royal Excel Mouscron | 3:0 | ||||
| 23. Round | 31/01/2021 | SV Zulte Waregem | - | KV Oostende | 2:1 | ||||
| 24. Round | 06/02/2021 | KV Oostende | - | Sint-Truidense VV | 3:1 | ||||
| 29. Round | 08/03/2021 | KAA Gent | - | KV Oostende | 1:0 | ||||
| 33. Round | 11/04/2021 | K Beerschot VA | - | KV Oostende | 1:2 | ||||
| 34. Round | 18/04/2021 | KV Oostende | - | Cercle Brugge | 1:1 |
Belgium