| 1. Round | 24/07/2021 | Amiens SC | - | AJ Auxerre | 1:2 | ||||
| 2. Round | 31/07/2021 | AC Ajaccio | - | Amiens SC | 3:1 |  |
|||
| 3. Round | 07/08/2021 | Amiens SC | - | US Quevilly-Rouen | 1:3 | ||||
| 4. Round | 14/08/2021 | EA Guingamp | - | Amiens SC | 0:2 | ||||
| 5. Round | 21/08/2021 | Amiens SC | - | FC Sochaux | 0:0 | ||||
| 6. Round | 28/08/2021 | Chamois Niortais | - | Amiens SC | 0:0 | ||||
| 7. Round | 11/09/2021 | Amiens SC | - | Rodez AF | 0:1 | ||||
| 8. Round | 18/09/2021 | Nîmes Olympique | - | Amiens SC | 3:3 | ||||
| 9. Round | 21/09/2021 | Amiens SC | - | Pau FC | 2:2 | ||||
| 10. Round | 24/09/2021 | AS Nancy Lorraine | - | Amiens SC | 1:1 | ||||
| 11. Round | 02/10/2021 | Amiens SC | - | Toulouse FC | 0:0 | ||||
| 12. Round | 16/10/2021 | Dijon FCO | - | Amiens SC | 1:0 | ||||
| 16. Round | 20/11/2021 | Havre AC | - | Amiens SC | 1:1 | ||||
| 17. Round | 03/12/2021 | Amiens SC | - | USL Dunkerque | 3:0 | ||||
| 18. Round | 11/12/2021 | Amiens SC | - | Grenoble Foot 38 | 4:1 | ||||
| 19. Round | 21/12/2021 | Paris FC | - | Amiens SC | 1:0 | ||||
| 20. Round | 19/01/2022 | Amiens SC | - | AC Ajaccio | 0:1 | ||||
| 22. Round | 22/01/2022 | Amiens SC | - | EA Guingamp | 3:0 | ||||
| 21. Round | 26/01/2022 | US Quevilly-Rouen | - | Amiens SC | 1:1 |
France
Senegal