| 2. Round | 01/08/2022 | Atlético Chiriquí | - | UD Universitario | 3:2 |  |
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| 3. Round | 06/08/2022 | San Francisco FC | - | Atlético Chiriquí | 0:0 |  |
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| 4. Round | 10/08/2022 | Independiente de La Chorrera | - | Atlético Chiriquí | 3:0 | ||||
| 5. Round | 15/08/2022 | Atlético Chiriquí | - | Veraguas United | 1:1 | ||||
| 1. Round | 18/08/2022 | Atlético Chiriquí | - | Herrera FC | 0:0 | |
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| 6. Round | 22/08/2022 | Atlético Chiriquí | - | Plaza Amador | 1:2 | ||||
| 7. Round | 28/08/2022 | Tauro FC | - | Atlético Chiriquí | 0:0 | |
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| 9. Round | 10/09/2022 | Árabe Unido | - | Atlético Chiriquí | 2:0 | |
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| 10. Round | 18/09/2022 | Atlético Chiriquí | - | Sporting San Miguelito | 0:0 | |
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| 11. Round | 25/09/2022 | Alianza | - | Atlético Chiriquí | 4:0 | ||||
| 12. Round | 27/09/2022 | Herrera FC | - | Atlético Chiriquí | 0:0 | ||||
| 13. Round | 03/10/2022 | UD Universitario | - | Atlético Chiriquí | 0:0 | ||||
| 14. Round | 09/10/2022 | Atlético Chiriquí | - | San Francisco FC | 0:4 | |
Panama