| 7. Round | 27/09/2021 | Denizlispor | - | Samsunspor | 2:3 |  |
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| 8. Round | 03/10/2021 | Samsunspor | - | Ümraniyespor | 1:1 | |
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| 9. Round | 16/10/2021 | Menemen Belediyespor | - | Samsunspor | 3:2 |  |
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| 10. Round | 23/10/2021 | Samsunspor | - | BB Erzurumspor | 0:0 | |
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| 11. Round | 30/10/2021 | Bandırmaspor | - | Samsunspor | 2:0 | ||||
| 12. Round | 06/11/2021 | Samsunspor | - | Manisa FK | 1:0 |
Ivory Coast