| 4. Round | 25/09/2010 | AE Paphos | - | APOEL Nikosia | 1:1 |  |
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| 7. Round | 23/10/2010 | APOEL Nikosia | - | AEK Larnaca | 1:0 | |
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| 8. Round | 30/10/2010 | Ethnikos Achna | - | APOEL Nikosia | 0:1 | |
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| 10. Round | 13/11/2010 | APOP Kinyras | - | APOEL Nikosia | 0:5 | |
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| 11. Round | 21/11/2010 | APOEL Nikosia | - | Doxa Katokopias | 3:1 | |
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| 13. Round | 04/12/2010 | AEL Limassol | - | APOEL Nikosia | 2:2 | |
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| 15. Round | 18/12/2010 | APOEL Nikosia | - | Enosis Neon Paralimni | 2:1 | |
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| 17. Round | 15/01/2011 | APOEL Nikosia | - | AE Paphos | 5:1 | |
North Macedonia