| Group B | 28/11/2021 | América de Cali | - | Millonarios | 2:1 |  |
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| Group B | 03/12/2021 | Millonarios | - | Alianza Petrolera | 3:0 |  |
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| Group B | 05/12/2021 | Deportes Tolima | - | Millonarios | 1:1 | ||||
| Group B | 10/12/2021 | Millonarios | - | Deportes Tolima | 1:1 | ||||
| Group B | 12/12/2021 | Alianza Petrolera | - | Millonarios | 0:1 | |
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| Group B | 17/12/2021 | Millonarios | - | América de Cali | 2:1 | |
Colombia