| 1. Round | 29/08/2021 | CD Calahorra | - | UD Logroñés | 0:0 | ||||
| 2. Round | 04/09/2021 | UD Logroñés | - | Racing Santander | 1:0 |  |
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| 3. Round | 11/09/2021 | Zamora CF | - | UD Logroñés | 1:4 | ||||
| 4. Round | 19/09/2021 | UD Logroñés | - | Real Unión | 1:0 | ||||
| 5. Round | 26/09/2021 | Athletic Club B | - | UD Logroñés | 3:1 | ||||
| 6. Round | 02/10/2021 | UD Logroñés | - | UD SS Reyes | 1:0 | ||||
| 7. Round | 10/10/2021 | UD Logroñés | - | SD Logroñés | 0:1 | ||||
| 8. Round | 17/10/2021 | Inter de Madrid | - | UD Logroñés | 2:2 | ||||
| 9. Round | 23/10/2021 | UD Logroñés | - | CF Talavera | 1:0 | ||||
| 10. Round | 31/10/2021 | RC Celta B | - | UD Logroñés | 0:1 | ||||
| 11. Round | 07/11/2021 | UD Logroñés | - | Deportivo La Coruña | 0:1 | ||||
| 12. Round | 14/11/2021 | CD Badajoz | - | UD Logroñés | 1:2 | ||||
| 13. Round | 21/11/2021 | CD Tudelano | - | UD Logroñés | 0:0 | ||||
| 14. Round | 26/11/2021 | UD Logroñés | - | Real Valladolid B | 3:2 | ||||
| 16. Round | 12/12/2021 | UD Logroñés | - | Extremadura UD | 1:3 | ||||
| 17. Round | 19/12/2021 | Unionistas CF | - | UD Logroñés | 4:0 |
Spain