| Group B | 19/08/2010 | Columbus Crew | - | CSD Municipal | 1:0 | ||||
| Group B | 27/08/2010 | CSD Municipal | - | Joe Public FC | 1:1 | ||||
| Group B | 15/09/2010 | CSD Municipal | - | Santos Laguna | 2:2 | ||||
| Group B | 24/09/2010 | Joe Public FC | - | CSD Municipal | 2:3 |  |
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| Group B | 30/09/2010 | CSD Municipal | - | Columbus Crew | 2:1 | ||||
| Group B | 20/10/2010 | Santos Laguna | - | CSD Municipal | 6:1 |
Guatemala