| 21. Round | 30/01/2022 | Lokomotiva Zagreb | - | Hrvatski Dragovoljac | 2:1 | ||||
| 22. Round | 05/02/2022 | HNK Rijeka | - | Lokomotiva Zagreb | 3:2 | ||||
| 27. Round | 11/03/2022 | HNK Šibenik | - | Lokomotiva Zagreb | 1:4 | ||||
| 28. Round | 19/03/2022 | Hajduk Split | - | Lokomotiva Zagreb | 4:0 | ||||
| 29. Round | 04/04/2022 | Lokomotiva Zagreb | - | Slaven Belupo | 3:1 | ||||
| 30. Round | 09/04/2022 | Hrvatski Dragovoljac | - | Lokomotiva Zagreb | 1:1 | ||||
| 31. Round | 16/04/2022 | Lokomotiva Zagreb | - | HNK Rijeka | 2:1 | ||||
| 32. Round | 23/04/2022 | NK Istra 1961 | - | Lokomotiva Zagreb | 2:2 | ||||
| 33. Round | 01/05/2022 | Lokomotiva Zagreb | - | Dinamo Zagreb | 1:1 | ||||
| 34. Round | 07/05/2022 | HNK Gorica | - | Lokomotiva Zagreb | 3:3 | ||||
| 35. Round | 15/05/2022 | NK Osijek | - | Lokomotiva Zagreb | 1:0 | ||||
| 36. Round | 20/05/2022 | Lokomotiva Zagreb | - | HNK Šibenik | 2:1 |  |
Croatia