| 2. Round | 29/07/2018 | FC DAC 1904 | - | MFK Zemplín Michalovce | 4:1 | ||||
| 4. Round | 11/08/2018 | Spartak Trnava | - | MFK Zemplín Michalovce | 3:0 | ||||
| 5. Round | 18/08/2018 | MFK Zemplín Michalovce | - | FK Senica | 1:1 | ||||
| 1. Round | 21/08/2018 | MFK Zemplín Michalovce | - | MŠK Žilina | 0:1 | ||||
| 9. Round | 22/09/2018 | FC Nitra | - | MFK Zemplín Michalovce | 2:1 | ||||
| 11. Round | 06/10/2018 | AS Trenčín | - | MFK Zemplín Michalovce | 1:2 | ||||
| 12. Round | 20/10/2018 | MŠK Žilina | - | MFK Zemplín Michalovce | 2:2 | ||||
| 14. Round | 03/11/2018 | Slovan Bratislava | - | MFK Zemplín Michalovce | 6:0 | ||||
| 15. Round | 11/11/2018 | MFK Zemplín Michalovce | - | Spartak Trnava | 1:0 | ||||
| 16. Round | 24/11/2018 | FK Senica | - | MFK Zemplín Michalovce | 2:4 | ||||
| 17. Round | 01/12/2018 | MFK Zemplín Michalovce | - | Zlaté Moravce | 3:0 | ||||
| 18. Round | 08/12/2018 | FK Železiarne Podbrezová | - | MFK Zemplín Michalovce | 0:1 |  |
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| 21. Round | 02/03/2019 | MFK Ružomberok | - | MFK Zemplín Michalovce | 0:0 |
Slovakia