| 16. Round | 22/01/2021 | Lierse Kempenzonen | - | Club NXT | 3:1 | ||||
| 17. Round | 31/01/2021 | KVC Westerlo | - | Lierse Kempenzonen | 2:0 | ||||
| 18. Round | 05/02/2021 | Union Saint-Gilloise | - | Lierse Kempenzonen | 2:1 | ||||
| 19. Round | 14/02/2021 | Lierse Kempenzonen | - | KMSK Deinze | 1:1 | ||||
| 21. Round | 28/02/2021 | Lierse Kempenzonen | - | RFC Seraing | 0:1 | ||||
| 22. Round | 05/03/2021 | Lierse Kempenzonen | - | Union Saint-Gilloise | 1:3 | ||||
| 23. Round | 12/03/2021 | KMSK Deinze | - | Lierse Kempenzonen | 3:0 |
Belgium