| 5. Round | 01/08/2022 | Unión Magdalena | - | Millonarios | 0:2 | ||||
| 6. Round | 06/08/2022 | Envigado FC | - | Unión Magdalena | 1:2 |  |
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| 7. Round | 13/08/2022 | Atlético Bucaramanga | - | Unión Magdalena | 1:0 | ||||
| 8. Round | 21/08/2022 | Unión Magdalena | - | Atlético Nacional | 2:2 | ||||
| 10. Round | 04/09/2022 | Unión Magdalena | - | Atlético Junior | 2:1 |  |
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| 11. Round | 10/09/2022 | Cortuluá | - | Unión Magdalena | 1:2 | ||||
| 15. Round | 04/10/2022 | Patriotas FC | - | Unión Magdalena | 3:1 |
Colombia
Panama