| 1. Round | 23/08/2021 | Apollon Limassol | - | Ethnikos Achna | 4:2 |  |
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| 2. Round | 11/09/2021 | Ethnikos Achna | - | PAEEK | 1:3 | ||||
| 8. Round | 31/10/2021 | AEK Larnaca | - | Ethnikos Achna | 1:0 | ||||
| 9. Round | 07/11/2021 | Ethnikos Achna | - | Omonia Nikosia | 0:2 | ||||
| 10. Round | 20/11/2021 | Paphos FC | - | Ethnikos Achna | 3:0 | ||||
| 11. Round | 26/11/2021 | Ethnikos Achna | - | Olympiakos Nikosia | 1:0 | ||||
| 12. Round | 06/12/2021 | Ethnikos Achna | - | Apollon Limassol | 0:1 | |
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| 13. Round | 11/12/2021 | PAEEK | - | Ethnikos Achna | 0:2 |  |
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| 14. Round | 18/12/2021 | Ethnikos Achna | - | Anorthosis Famagusta | 0:2 | |
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| 15. Round | 03/01/2022 | Ethnikos Achna | - | Doxa Katokopias | 0:1 | |
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| 16. Round | 08/01/2022 | Aris Limassol | - | Ethnikos Achna | 2:1 | ||||
| 19. Round | 29/01/2022 | Ethnikos Achna | - | AEK Larnaca | 0:0 |
Croatia