| 1. Round | 05/02/2023 | Montevideo City Torque | - | Danubio | 1:1 | ||||
| 2. Round | 12/02/2023 | Danubio | - | Liverpool | 1:1 | ||||
| 4. Round | 26/02/2023 | Danubio | - | Plaza Colonia | 5:0 | ||||
| 5. Round | 03/03/2023 | Racing | - | Danubio | 1:1 | ||||
| 6. Round | 12/03/2023 | Danubio | - | CA Cerro | 1:0 | ||||
| 7. Round | 19/03/2023 | Boston River | - | Danubio | 3:3 | ||||
| 12. Round | 23/04/2023 | Fénix | - | Danubio | 2:1 | ||||
| 13. Round | 29/04/2023 | Danubio | - | Montevideo Wanderers | 0:2 | ||||
| 14. Round | 07/05/2023 | La Luz | - | Danubio | 3:1 | ||||
| 15. Round | 14/05/2023 | Danubio | - | Defensor Sporting | 1:1 |
Colombia